Ok, this would seem as a very stupid problem but I have no reason why it happening.
I am in a Developer Pro Sandbox logged in as System Administrator. I need to change the create/edit permissions for account and contacts and also disable the "View the App Setup and Administrative Settings pages" for the Marketing User profile.
However when I go to the profile and respective tabs, the checkboxes for those settings are locked in (disabled).
You can see above the Read, Create, Edit, Delete checkboxes are disabled so I cant change those permissions.
The View the App Setup and Administrative Settings checkbox is also disabled.
Is it because of the fact that I am in a Developer Pro Sandbox so it won't let me change these settings for other profiles?