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Ok, this would seem as a very stupid problem but I have no reason why it happening.

I am in a Developer Pro Sandbox logged in as System Administrator. I need to change the create/edit permissions for account and contacts and also disable the "View the App Setup and Administrative Settings pages" for the Marketing User profile.

However when I go to the profile and respective tabs, the checkboxes for those settings are locked in (disabled).

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You can see above the Read, Create, Edit, Delete checkboxes are disabled so I cant change those permissions.

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The View the App Setup and Administrative Settings checkbox is also disabled.

Is it because of the fact that I am in a Developer Pro Sandbox so it won't let me change these settings for other profiles?

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    This is an OOTB Profile and you are limited in the changes that can be done; common practice is to clone Marketing Profile and call it MyCompany Marketing Profile. Or, use another profile with limited features/permissions and extend with permission sets - assigning users to the permission sets
    – cropredy
    Commented Jun 25, 2018 at 17:19
  • Thank you. I had forgotten about these standard profiles and kept wondering what was going on.
    – codeinprogress
    Commented Jun 26, 2018 at 3:01

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This is an OOTB Profile and you are limited in the changes that can be done;

Common practice is to clone Marketing Profile and call it MyCompany Marketing Profile.

Or, use another profile with limited features/permissions and extend with permission sets that grant the relevant Marketing Profile permissions - then assign users to the permission sets.

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