I have an email I am creating in content builder and I cannot change the padding in layout settings at the MOBILE level to whatever i want. I know this can be done using custom HTML, but is there a way to make it as user friendly as possible by doing it in the interface?
Your question is very generic. I will try to answer in scenarios:
If you want to edit the padding for mobile in terms of template. Then you can go to
Emails > Design Tab > Mobile Styles > You can choose the padding from interface.
Below is the screenshot of it:
If you want to edit the padding for some blocks, then go to the
blocks > HTML Tab and then try to use
!important in In-line css for padding.
Let me know if this helps.