Is this possible to edit values of Checkboxes:

Update Reminder Setup:
- Enable Update Reminders for My Organization 
- Automatically Activate Reminders for Users with Direct Reports 

by some API, if I would want to write some app eg. in Java?


It is possible to change some settings via the Metadata API, but "Enable Update Reminders" is one that isn't supported.

Reference: https://developer.salesforce.com/docs/atlas.en-us.api_meta.meta/api_meta/meta_unsupported_types.htm?search_text=update%20reminders

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