Are there any Pro/Con for Salesforce Sends using Marketing Cloud Connect between Reports and Campaigns?
Why would you send to a Report versus send to a Campaign?
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I believe that Report get refreshed automatically at the time of sending. Without Process Builder the update a camapaign, the Campaigns will have the same number of members.
Also something to look at is the ROI. SFMC is not strong there so leveraging campaign and assigning a budget can help for reporting.