When you build a Salesforce site.com (not force.com site) pages do you build directly in production ? In other words, can you build site.com pages and artifacts in a Sandbox and deploy them to production org through tradition Force.com IDE, change set or via ant scripts ?
Looking for best practices around the development methodology for Site.com.
Yes, the traditional model is to build Site.com sites directly in the production org. Site.com has its own "sandbox like" environment in the way that your in-development version of the site is not publically available until after you publish.
Sandbox support for Site.com is introduced in Winter'14, see the Release Notes