Admin users have the ability to modify the
Page Layout and can easily remove a specific
Visualforce Page from it. Is there any way to prevent this from happening? If not, what steps should I take to prevent Admin users from removing the
There is no mechanism to make a
Visualforce Page "required" on a
Page Layout. You are going to have to rethink your requirements and approach this from an admin training perspective. If you train your admins not to remove this page from the layout, you should be able to trust them to follow your instruction as long as they are capable professionals.