I would like to make a TriggeredSendDefintion which once a day [say at 9am] grabs everyone in its SendSourceDataExtension, and send them an email. Is this possible with a TriggeredSendDefinition?



No, not with a TriggeredSendDefinition. Triggers only fire via API call and you have to send the audience with the call.

A User-Initiated Send is what you're looking for. It's a combination of an audience (List, Data Extension or Filter) and an email.

You can automate the send of a User-Initiated Send Definition on some interval using a Program or Automation in Automation Studio.

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