Per today's Summer 21 release webinar, you will need to do two things
Add a new import:
import { CloseActionScreenEvent } from 'lightning/actions';
Then add a simple method to close it:
closeQuickAction() {
this.dispatchEvent(new CloseActionScreenEvent());
}
You can then call that and it will close the quick action. More details here
H/T to Fabien Taillon for the heads up on this one