You need to combine and (&&) and or (||) operators, like this:
if(objQuote.records.SYS_Account_Credit_Application__c !== 'No' &&
(objQuote.records.CAA_Agreement__c ===== null || !objQuote.records.SYS_CAA_Active_Check__c !== 'Active')) {
Note here that you can apply De Morgan's Laws of Boolean Operations: NOT A OR NOT B can be expressed as NOT (A AND B).
if(objQuote.records.SYS_Account_Credit_Application__c !== 'No' &&
!(objQuote.records.CAA_Agreement__c !== null && objQuote.records.SYS_CAA_Active_Check__c == 'Active')) {